Fatal attractions that trigger inflammation and drive atherosclerotic disease

H Sharma, K Mossman… - European Journal of …, 2024 - Wiley Online Library
… The lysosomes contain iron derived structures which … that HCMV infected endothelial cells
attenuates endothelialInfection with Chlamydia pneumoniae accelerates the development of …

[HTML][HTML] Chlamydia trachomatis and Chlamydia pneumoniae Interaction with the Host: Latest Advances and Future Prospective

M Di Pietro, S Filardo, S Romano, R Sessa - Microorganisms, 2019 - mdpi.com
trachomatis infection increases the risk of acquiring and transmitting human … to induce
in macrophages, platelets, endothelial cells and VSMCs an increased production of pro-…

Toll-like receptor 3 deficiency leads to altered immune responses to Chlamydia trachomatis infection in human oviduct epithelial cells

JZ Xu, R Kumar, H Gong, L Liu… - Infection and …, 2019 - Am Soc Microbiol
… Our data showing significant increases in OPN production in TLR3-deficient hOE cells
immune protein that limits bacterial growth by sequestering iron-containing siderophores (85). …

[HTML][HTML] COVID-19 as part of the hyperferritinemic syndromes: the role of iron depletion therapy

C Perricone, E Bartoloni, R Bursi, G Cafaro… - Immunologic …, 2020 - Springer
… More specifically, CMV requires iron in order to induce an increase in the … , iron is able to
increase the in vitro production of IL-6 by endothelial cells following infection with Chlamydia

[HTML][HTML] Gram-negative bacteria and their lipopolysaccharides in Alzheimer's disease: Pathologic roles and therapeutic implications

H Kim, S Kim, SJ Shin, YH Park, Y Nam, C Kim… - Translational …, 2021 - Springer
… as Proteobacteria and Chlamydophila pneumonia, have been … brain endothelial cells induces
necrosis of endothelial cells [55… K1 promotes bacterial transcytosis across the endothelium

[HTML][HTML] … of the cyclin-dependent kinase inhibitor p27 as a putative candidate for transformation in Chlamydia trachomatis infected mesenchymal stem cells

MA Abu-Lubad, W Al-Zereini, MA Al-Zeer - AIMS microbiology, 2023 - ncbi.nlm.nih.gov
… cyclin D1, a complex that promotes the cell transition from the G1 … pneumoniae infection of
human endothelial cells induces … Furthermore, the human cytomegalovirus strain DB was able …

Pre-eclampsia and eclampsia pathogenesis utilizes iron released by a hemolytic protozoan parasite

K Roe - Medical Hypotheses, 2023 - Elsevier
… , which was suppressed by iron deprivation. The newly … iron boosts the pathogen infections,
impairs important immune cells and can be recycled in oxidation/reduction reactions which …

Endometrial responses to bacterial and viral infection: a scoping review

CV Lindsay, JA Potter, AA Grimshaw… - Human …, 2023 - academic.oup.com
responses to Escherichia coli and Chlamydia trachomatis, … Endometrial responses have
only been studied in response … and increase the number of CD4+/TGFβ1+ regulatory T cells, …

[HTML][HTML] Statins: a viable candidate for host-directed therapy against infectious diseases

SP Parihar, R Guler, F Brombacher - Nature Reviews Immunology, 2019 - nature.com
… In addition, endothelial cells increase their expression of … of both simvastatin and an iron
chelator directly on the cornea … and dissemination of Chlamydia pneumoniae in mice 80 . …

[HTML][HTML] Viral hepatitis and iron dysregulation: Molecular pathways and the role of lactoferrin

R Mancinelli, L Rosa, A Cutone, MS Lepanto… - Molecules, 2020 - mdpi.com
… is lined with different specialized cells such as the sinusoidal endothelial cells (LSECs), the
… a significant decrease of iron export from cells into plasma and an increase of intracellular …